糟糕wwk 发表于 2025-3-10 16:04:43

发现1例!毒性是砒霜的68倍!千万警惕…

<!----><style type="text/css">html{font-size:375%}</style><link href="https://pics-app.cnyw.net/static/publish/css/style.css?v=20240712" rel="stylesheet" position="1" data-qf-origin="/static/publish/css/style.css?v=20240712"><!--    付费贴-->    <div class="preview_article ">            <!---->    <section><section><section><p class="empty_paragraph" style="text-align: center; -webkit-tap-highlight-color: transparent; outline: 0px; letter-spacing: 0.544px; caret-color: rgba(0, 0, 0, 0); color: #222222; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;">&nbsp;</p></section><section><section><p style="text-align: center;"><span style="letter-spacing: 0.544px; caret-color: red; font-size: 15px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;">最近是呼吸道传染病高发期</span></p></section><section style="-webkit-tap-highlight-color: transparent; outline: 0px; letter-spacing: 0.544px; background-color: #ffffff; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px; visibility: visible;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px; visibility: visible;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px; visibility: visible;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px; visibility: visible;"><section><p style="text-align: center; max-inline-size: 100%; cursor: text; visibility: visible;"><span style="visibility: visible; font-size: 15px;">大家身边有不少人</span></p><p style="text-align: center; max-inline-size: 100%; cursor: text; visibility: visible;"><span style="visibility: visible; font-size: 15px;">都中招&ldquo;甲流&rdquo;了</span></p><p style="text-align: center; max-inline-size: 100%; cursor: text; visibility: visible;"><span style="visibility: visible; font-size: 15px;">无论是刚感染还是刚痊愈</span></p><p style="text-align: center; max-inline-size: 100%; cursor: text; visibility: visible;"><span style="visibility: visible; font-size: 15px;">都要格外注意!</span></p><p style="text-align: center; max-inline-size: 100%; cursor: text; visibility: visible;">&nbsp;</p><section><section><section style="margin-bottom: unset;"><section style="text-align: center; margin-top: 10px; margin-bottom: 10px;"><section style="display: inline-block; margin-bottom: unset;"><section style="background-color: #429ed7; border-radius: 6px; padding: 5px 18px; color: #ffffff; letter-spacing: 2px; font-size: 15px; margin-bottom: unset;"><p><strong style="letter-spacing: 0.578px;">流感还能引起肺&ldquo;发霉&rdquo;?</strong></p></section><section style="margin-top: -15px; margin-bottom: unset;"><section style="width: 15px; height: 15px; border-top: 3px solid #ffffff; border-left: 3px solid #ffffff; margin-left: auto; margin-bottom: unset; overflow: hidden; line-height: 0;"></section></section></section></section></section></section></section><p>&nbsp;</p><p><span style="font-size: 15px;">前段时间,今年52岁的朱先生因<span style="color: #007aaa;"><strong>&ldquo;胸闷气促7天&rdquo;</strong></span>到医院就诊,诊断为<span style="color: #007aaa;"><strong>甲流。</strong></span></span></p><p>&nbsp;</p><p><span style="font-size: 15px;">可经过<strong><span style="color: #007aaa;">一番治疗后,病情却不见好转,反而进一步加重,</span></strong>患者被紧急转至上海交通大学医学院附属瑞金医院嘉定院区急诊就诊。</span></p><p>&nbsp;</p><p><span style="font-size: 15px;">入院时,朱先生的病情非常危重,<span style="color: #007aaa;"><strong>持续高热、急性呼吸衰竭、电解质紊乱、休克等,</strong></span>在抢救室紧急气管插管后,急诊科陆一鸣主任当机立断将患者紧急收入急诊重症监护室接受进一步治疗。</span></p><p>&nbsp;</p><p><span style="font-size: 15px;">病人体重近300斤,当时血压在大剂量升压药物维持下也只有60/40mmHg,心跳高达150次/分,全身花斑,四肢湿冷,血糖22mmol/l,<span style="color: #007aaa;"><strong>血气分析pH:6.9,提示严重酸中毒(正常值7.35~7.45),休克。</strong></span></span></p><p>&nbsp;</p><p><span style="font-size: 15px;">针对如此危重病情,主治医生迅速抓住当前主要关键点:糖尿病酮症酸中毒,感染性休克,甲型流感病毒性肺炎等,并启动目标导向性液体复苏,控制血糖,连续性血液肾脏替代治疗(CRRT),调节酸碱平衡等综合治疗。同时进行脉搏指示连续心输出量监测(PICCO)和床旁心脏超声,监测心功能及指导液体复苏。</span></p><p>&nbsp;</p><p style="color: #000000; letter-spacing: 1px; line-height: 1.75em;"><img class="rich_pages wxw-img" style="vertical-align: baseline; visibility: visible !important; width: 660px !important;" src="https://pics-app.cnyw.net/FltF_bzid8EqQBWdyYOm-01YyV_t" alt="图片" /></p><p style="color: #000000; letter-spacing: 1px; line-height: 1.75em;">&nbsp;</p><p><span style="font-size: 15px;">经过急诊重症监护室医护团队初步治疗,朱先生的酮症酸中毒、感染性休克有好转迹象,但患者病情仍然不容乐观:<strong><span style="color: #007aaa;">如何控制重症肺炎和急性呼吸衰竭等成为主要矛盾。</span></strong></span></p><p>&nbsp;</p><p><span style="font-size: 15px;">陆主任在仔细分析病情和影像学检查后,<strong><span style="color: #007aaa;">高度怀疑朱先生可能合并侵袭性肺曲霉病感染,</span></strong>立即安排行床旁纤维支气管镜检查及肺泡灌洗液查病原体,终于揪出&ldquo;真凶&rdquo;&mdash;&mdash;<strong><span style="color: #007aaa;">流感相关性肺曲霉病(IAPA)</span></strong>,随后立刻针对该患者调整治疗方案,启动抗霉菌治疗。</span></p><p>&nbsp;</p><p><span style="font-size: 15px;">在急诊重症监护室经过近1个月的治疗后,朱先生病情逐渐稳定下来,并康复出院。</span></p><p>&nbsp;</p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 15px;"><strong>肺也会发霉吗?</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">答案是&mdash;&mdash;</span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 15px;"><strong>会!而且这种发霉长毛</strong><br /></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 15px;"><strong>对肺部组织的破坏力极大</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 15px;"><strong>短期内可将肺部掏空</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">治疗起来尤为困难</span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;">&nbsp;</p><section style="margin-bottom: unset;"><section><section style="border: 1px solid #047c7a;"><section><section style="width: 90%; margin-right: auto; margin-left: auto; max-width: 90% !important;"><section style="margin-bottom: 10px;"><section style="color: #333333; letter-spacing: 1px; line-height: 26px; text-align: left; font-size: 12px;"><p style="color: #000000; line-height: 1.75em; text-align: center;">&nbsp;</p><p style="color: #000000; line-height: 1.75em; text-align: center;"><span style="color: #000000; font-size: 17px;">&nbsp;<strong><span style="letter-spacing: 0.578px;">什么是流感合并肺曲霉病?</span></strong></span></p><p style="color: #000000; line-height: 1.75em; text-align: center;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="font-size: 15px;"><span style="letter-spacing: normal;">曲霉菌是一种真菌,</span><span style="letter-spacing: normal; color: #007aaa;"><strong>它被世界卫生组织列为</strong><strong>一等致癌物质</strong><strong>,其毒性是砒霜的</strong><strong>68倍</strong><strong>。</strong></span><span style="letter-spacing: normal;">它广泛存在于自然环境中的真菌,土壤、空气、腐烂的植被中都能找到它的身影。曲霉菌比较常见的可分为三种:烟曲霉菌、黑曲霉菌、黄曲霉菌,曲霉菌在临床上引起的感染称之为曲霉病。正常情况下,我们的免疫系统可以抵御曲霉菌的侵袭。</span></span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="font-size: 15px;"><span style="letter-spacing: normal;">然而,当人体免疫力低下时,例如流感病毒感染后,曲霉菌就可能&ldquo;趁虚而入&rdquo;,</span><span style="letter-spacing: normal; color: #007aaa;"><strong>破坏呼吸道纤毛细胞、侵袭肺部并迅速扩散,导致各种临床症状,对于健康有很大的危害甚至危及生命</strong>。</span></span></p></section></section></section><section style="width: 90%; margin-right: auto; margin-left: auto; max-width: 90% !important;"><section style="margin-bottom: 10px;"><p style="font-size: 10px; line-height: 10px;">&nbsp;</p><p style="font-size: 10px; line-height: 10px; text-align: center;">&nbsp;</p><p style="font-size: 10px; line-height: 10px; text-align: center;"><strong><span style="font-size: 17px;">为什么流感患者容易合并曲霉菌感染? &nbsp;</span></strong></p><section style="color: #333333; letter-spacing: 1px; line-height: 26px; text-align: left; font-size: 12px;"><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">1. 流感病毒损伤呼吸道黏膜,为曲霉菌的入侵创造了条件。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">2. 流感导致免疫力下降,削弱了机体对曲霉菌的抵抗力。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">3. 部分流感患者使用糖皮质激素,也可能增加曲霉菌感染的风险。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">4.合并基础疾病的患者,包括免疫抑制状态以及慢性呼吸系统疾病、慢性肝肾疾病、糖尿病、实体肿瘤、血液系统肿瘤等基础疾病。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em; text-align: center;"><strong><span style="letter-spacing: normal; font-size: 17px;">有哪些症状? &nbsp; &nbsp;&nbsp;</span></strong></p></section></section></section><section style="width: 90%; margin-right: auto; margin-left: auto; max-width: 90% !important;"><section style="margin-bottom: 10px;"><section style="color: #333333; letter-spacing: 1px; line-height: 26px; text-align: left; font-size: 12px;"><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">流感合并曲霉菌感染的症状与普通流感相似,容易造成误诊漏诊。但如果出现以下情况,需高度警惕:</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">1.持续高热不退,常规退烧药效果不佳。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">2.咳嗽加重,出现胸痛、呼吸困难等症状。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">3.咳出带血丝或棕褐色的痰液。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">4.出现鼻塞、流脓涕、面部疼痛等鼻窦炎症状。</span></p></section></section></section><section style="width: 90%; margin-right: auto; margin-left: auto; max-width: 90% !important;"><section style="margin-bottom: 10px;"><p style="font-size: 10px; line-height: 10px;">&nbsp;</p><section style="color: #333333; letter-spacing: 1px; line-height: 26px; text-align: left; font-size: 12px;"><p style="color: #000000; line-height: 1.75em; text-align: center;"><span style="font-size: 17px;"><strong>如何预防流感合并曲霉菌感染?</strong></span></p><p style="color: #000000; line-height: 1.75em; text-align: center;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">1. 积极预防流感:接种流感疫苗,勤洗手,戴口罩,避免去人群密集场所。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">2. 增强免疫力:保持充足睡眠,均衡饮食,适量运动。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">3. 保持环境清洁干燥:定期开窗通风,避免接触发霉变质的物品。</span></p><p style="color: #000000; line-height: 1.75em;">&nbsp;</p><p style="color: #000000; line-height: 1.75em;"><span style="letter-spacing: normal; font-size: 15px;">4. 合理使用药物:避免滥用抗生素和糖皮质激素。</span></p></section></section></section></section></section></section><section><p>&nbsp;</p></section></section><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 18px;"><strong>流感季当心&ldquo;雪上加霜&rdquo;</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 18px;"><strong>大家一定要注意防护</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;"><span style="letter-spacing: normal; color: #007aaa; font-size: 18px;"><strong>警惕流感合并曲霉菌感染</strong></span></p><p style="text-align: center; color: #000000; letter-spacing: 1px; line-height: 1.75em;">&nbsp;</p></section></section></section></section></section></section><section style="-webkit-tap-highlight-color: transparent; outline: 0px; letter-spacing: 0.578px; background-color: #ffffff; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px;"><section style="-webkit-tap-highlight-color: transparent; outline: 0px;"><p style="text-align: right; -webkit-tap-highlight-color: transparent; outline: 0px; letter-spacing: 0.544px;"><span style="-webkit-tap-highlight-color: transparent; outline: 0px; color: #888888; letter-spacing: 0.408px; font-size: 12px;">来 源:荆楚网、新闻坊、湖南省第三人民医院</span></p><p style="-webkit-tap-highlight-color: transparent; outline: 0px; letter-spacing: 0.544px;">&nbsp;</p></section></section></section></section></section></section><p style="display: none;">&nbsp;</p>    <!----></div>            

张香云 发表于 2025-3-11 03:52:09

刚听到人有这种病

小鱼nice 发表于 2025-3-11 13:29:48

进来学习一下
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